![]() ![]() Wachtell, Lipton, Rosen & Katz is serving as legal advisor to Regeneron. Centerview Partners LLC served as financial advisor and Goodwin Procter LLP served as legal counsel to Checkmate. At this time, there is no change to Regeneron's 2022 GAAP and non-GAAP financial guidance as a result of this transaction. Consequently, the total acquisition cost allocated to the acquired in-process research and development is expected to be expensed in the second quarter of 2022 and will be included in non-GAAP financial results. Regeneron anticipates accounting for this transaction as an asset acquisition. As a result of the acquisition, Checkmate common stock have ceased to be traded on the Nasdaq Global Market. Following its acceptance of the tendered shares, Regeneron completed its acquisition of Checkmate through a second step merger of Scandinavian Acquisition Sub, Inc. with and into Checkmate. All of the conditions of the offer have been satisfied, and Regeneron has paid $10.50 per share (without interest) for all shares that were validly tendered, which is the same price as in the tender offer. The tender offer by Regeneron for shares of Checkmate expired one minute after 11:59 p.m., Eastern Time, on Friday, May 27, 2022. Broadridge Corporate Issuer Solutions, Inc., the depository and paying agent for the tender offer, advised Regeneron that as of the tender offer expiration, a total of 18,471,314 shares had been validly tendered and not validly withdrawn, representing approximately 83.8% of the outstanding shares. With Libtayo ® (cemiplimab) as our anti-PD-1 backbone and a differentiated scientific approach, Regeneron is well positioned to make meaningful progress for people with cancer." "Our increasingly diverse portfolio enables strategic flexibility and creativity as we advance monotherapy and combination candidates for difficult-to-treat cancers. ![]() Schleifer, M.D., Ph.D., President and Chief Executive Officer of Regeneron. "As we continue to deepen and expand our efforts in immuno-oncology, the acquisition of Checkmate adds a potentially best-in-class clinical asset, as well as a promising underlying technology platform in the VLP delivery system," said Leonard S. TARRYTOWN, N.Y., May 31, 2022 /PRNewswire/ - Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that it has successfully acquired Checkmate Pharmaceuticals, Inc., deepening its commitment to immuno-oncology and adding a new modality to the company's portfolio of potential combination-ready approaches for difficult-to-treat cancers.Ĭheckmate's lead investigational candidate, vidutolimod, is an advanced generation CpG-A oligodeoxynucleotide Toll-like receptor 9 (TLR9) agonist delivered in a virus-like particle (VLP) and has demonstrated clinical responses as a monotherapy in patients with PD-1 refractory melanoma. The Chase Group is proud to partner with Checkmate and contribute to their success as they work to harness the power of the immune system to combat cancer.Acquisition strengthens Regeneron's innovative portfolio of immuno-oncology candidates and diversified approach to cancer treatment Osei Tutu joins a team of scientists, physicians, and life sciences entrepreneurs who are dedicated to discovering and developing new approaches to fighting cancer. A growing body of promising clinical data demonstrates its potential to address the unmet need for patients whose cancers are resistant to immunotherapeutic agents. Checkmate is investigating their lead candidate, vidutolimod, across multiple tumor types in combination with checkpoint inhibitor immunotherapies in melanoma and non-melanoma skin cancers and head and neck cancer. Checkmate Pharmaceuticals is a clinical-stage biotechnology company focused on developing its proprietary technology to harness the power of the immune system to combat cancer. Osei Tutu responsibility for the development and execution of Checkmate’s global regulatory strategy as the team’s regulatory expert. Osei Tutu brings valuable regulatory experience in the immune-oncology landscape to the team at Checkmate as they keep their focus on important regulatory milestones for vidutolimod. ![]() The Chase Group is pleased to announce the successful recruitment of Elvis Osei Tutu, PharmD, as the Vice President, Head of Regulatory Affairs at Checkmate Pharmaceuticals. ![]()
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In addition, lanes to assist drivers getting on and off the freeway (auxiliary lanes) will be constructed in selected locations. The project includes two tolled express lanes in each direction. The transportation authority’s project will widen the 10 Freeway between the Los Angeles/San Bernardino County line and the 15 Freeway, a distance of about 10 miles. Feds step in, make 10 Freeway Express Lanes in San Bernardino County a step closer to reality.Watch for 10 Freeway lane closures in Montclair, Ontario, Rancho Cucamonga.Why these Montclair residents oppose the 10 Freeway toll lanes.Euclid Avenue bridge construction at the 10 Freeway in Ontario continues, when will it be done?.“In other words, don’t do anything other than driving and be aware of the road conditions.” Related links ![]() “My advice is slow down, avoid any distractions like keeping your phone away,” Rawls said. “You are going to get to your destination, just get there safe,” Lambert added. ![]() Since this project has been underway for more than a year, regular commuters may be numb to the lane switching and orange cones.Įxtra, focused CHP patrols, plus a barrage of on-site portable signs, media and social media messages about construction detours aim to reach into the mindset of the person behind the wheel, Lambert said. 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If you’re selling beauty products in your business or as an online retailer, Alibaba is the go-to online site. If you’re looking for beauty products for daily use (and you’re almost out), stick with Amazon. There is no same-day shipping with Alibaba, and consumers can sometimes perceive purchases as lower quality. However, unlike Amazon, don’t expect that affordable price to come with quick delivery. It also typically comes with lower minimums for businesses purchasing items in bulk. Want the latest style of graphic tees, personalized jewelry, or tech at affordable prices?Īlibaba and their sister company, AliExpress is the perfect service provider.Īs a company based in China, the overseas aspect ensures competitive pricing on almost all products. Coming in at around $109.48 billion USD in 2021, It is the world’s number one business marketplace. Much like Amazon, A libaba is an online marketplace with an extensive range of items. Selling on Amazon is a good way to dip your toe into the ecommerce business, but I wouldn’t go in with high expectations. Sellers on Amazon make little to nothing, especially compared to the company’s startling revenue that only seems to be increasing. While Amazon is dominated the world of ecommerce, its sellers may tell a different story. Within the past few years, Amazon has stepped up its game with additions like Amazon Fashion, Amazon Echo, Ring Devices, and other smart technology! While Amazon is not necessarily known for the best customer service or rock bottom prices, it is undoubtedly one of the best online shopping sites that will deliver what you need (regardless of what that is) in record time. Lastly, Amazon developed (and patented) the “buy now” button, making it ridiculously easy to purchase what you want quickly. Prime is a membership option that gives participants exclusive access to everything from two-day shipping (or as fast as the same day) to discounts at other retailers (like Whole Foods) and video and music streaming. In addition to an endless selection, Amazon included arguably some of the fastest shipping times thanks to Prime. In 2021, this ecommerce giant raked in $469.8 billion in revenue. ![]() As an online marketplace, Amazon allows you to seamlessly shop through everything from toilet paper to collections from luxury brands and designer fashion (like Oscar de la Renta).Īlthough it started as an online bookstore, Amazon soon became much more – to the point that it’s hard to imagine life without it. They offer a huge selection, quick shipping, a valuable membership option, and that all-too-easy buy now button that speeds up the checkout.Īmazon doesn’t directly compete with independent designers it hosts them. Amazon has revolutionized the way we shop – for the better. 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